Lin Lab The Bytes of Minds Lab - Research


Welcome to the Lin Lab (Bytes of Minds Lab)! We are an interdisciplinary research group at the Icahn School of Medicine at Mount Sinai in the Departments of AI, psychiatry, and neuroscience. Based within the #1 hospital and the biggest hospital network in New York, we aim to push the boundaries of Computational Psychiatry and Neuro-AI by creating adaptive, intelligent systems powered by multi-modal foundation models such as large language models that can eventually both deepen our understanding of the mind and enhance mental health care in a scalable way.

Our Mission

The human brain is a powerful organ, enabling us to think, feel, and interact in complex ways. Yet, its workings and the nature of the mind remain partly mysterious. Our mission is to unravel these complexities by developing AI inspired by the brain's structure and function in social setting. We aim to create autonomous agent-based systems and foundation models of the brain that learn, adapt, and reason in ways that reflect the human mind, ultimately solving real-world challenges, interacting naturally with humans, and supporting mental health through advanced diagnostic and therapeutic tools.



Key Research Areas



Ongoing Research Directions

1. Computational cognitive models and neural dynamics focused on perception, memory, and social learning
2. Neuro-inspired and neurosymbolic AI architectures for adaptive learning
3. Real-time, multi-modal, and autonomous AI interfaces for clinical care, including AI companions, large language models, and psychometric assessments
4. Brain-computer interfaces, extended realities, and embodied cognition
5. Privacy-preserving AI solutions and societal impacts for secure healthcare applications

What we have built

Our work runs in production, not only in papers. We deployed an LLM voice agent for patient health coaching inside a major US hospital network, through IRB, clinical governance and security review. We co-direct the Therapeutic Alliance AI core of the $20M NIH IMPACT-MH consortium across 6 sites, covering 2,000+ patients over 5 years. Our methods work is published in PNAS, eLife, Nature Translational Psychiatry, and presented at AI conferences such as NeurIPS, AAAI, IJCAI, ICML, and AAMAS, and our code is open source on GitHub.

The lab's books are Privacy & Security in Large Language Models (O'Reilly, 2025) and Reinforcement Learning Methods in Speech and Language Technology (Springer, 2024).

If you want to work with us, or on something adjacent, get in touch.

Lin Lab The Bytes of Minds Lab - Publications


The publications can be grouped or (Books, Manuscripts or preprints, Journal articles, Conference proceedings, Extend abstracts and Patents). For other insights, please refer to our Google Scholar page.